The Nucleic Acid Modification Database

5-formyluracil

Description

A pyrimidone resulting from the formal oxidation of the alcoholic hydroxy group of 5-hydroxymethyluracil to the corresponding aldehyde. It is a major one-electron photooxidation product of thymine in oligodeoxynucleotides.

Basic Information

Comman Name	5-formyluracil
Symbol	5fU
Chemical Formula	C5H4N2O3
Nucleoside Mass	140.1

Locations and Contents

Modification	Organisms or Cells	Contents	References
5fU	mESCs	0.0002% [5fU/dN]	https://pubmed.ncbi.nlm.nih.gov/24838012/
5fU	Human thyroid carcinoma tissues	0.001% [5fU/dN]	https://pubmed.ncbi.nlm.nih.gov/28693723/

Modification Enzymes and Reactions

Modification Enzymes:KRuO4、NaOH、H2O

Reference:https://pubmed.ncbi.nlm.nih.gov/25946119/

Modification Enzymes:NgTET1

Reference:https://pubmed.ncbi.nlm.nih.gov/25831492/